Louis Pasteur

French chemist and microbiologist, 1822-1895

Pasteur was renowned for his discoveries of the principles of vaccination, microbial fermentation and pasteurization. He is remembered for his remarkable breakthroughs in the causes and preventions of diseases, and his discoveries have saved countless lives ever since. He reduced mortality from puerperal fever, and created the first vaccines for rabies and anthrax. His medical discoveries provided direct support for the germ theory of disease and its application in clinical medicine. He is best known to the general public for his invention of the technique of treating milk and wine to stop bacterial contamination, a process now called pasteurization. He is regarded as one of the three main founders of bacteriology, and is popularly known as the „father of microbiology“.

Source: Wikipedia

Pasteur, Louis

chimiste et biologiste français (1822-1895). 3 annotations autographes signées « L. Pasteur » et « L.P » en marge et en troisième page d’une LAS de Henri de Marliave, adressée à Louis PASTEUR. Paris. 4to. 2 1/4 pages.
$ 5,117 / 4.500 € (44539)

Document fort intéressant  où Pasteur réfléchit aux solutions à apporter au problème de la conservation du cèpe et ses conséquences sur sa commercialisation. Lettre de Marliave à Pasteur : «Monsieur Pasteur, Dans certaines contrées de la France et principalement dans le Midi, on fait une très grande consommation de cèpe, au printemps et à l’automne de chaque année. Le champignon, comme vous le savez, est fort nutritif, et ne fait aucun mal lorsqu’on en use avec modération, et qu’il se trouve dans un bon état de consommation.

Il n’en est pas malheureusement de même lorsqu’il a perdu sa première fraicheur. Il devient alors un vrai poison et peut occasionner de véritables empoisonnements qui sont souvent mortels. En général, les cèpes n’arrivant sur le marché qu’après avoir voyagé pendant un temps plus ou moins long, perdent leur première fraicheur ; ils se décomposent et offrent un vrai danger pour la santé publique, lorsqu’ils arrivent à destination. Plusieurs négociants de Toulouse m’ont prié de m’adresser à vous pour vous demander de vouloir bien nous indiquer s’il existe un moyen d’empêcher la fermentation et la décomposition des cèpes pendant les deux ou trois jours d’intervalle qui existent généralement entre la récolte et la vente. Si ce moyen existe, il faudrait pour qu’il soit efficace, qu’il réunisse les conditions suivantes :  1° Etre peu coûteux 2° Conserver les champignons entiers avec la queue ou du moins une partie de la queue 3° Ne laisser aucune trace sur le cèpe qui doit avoir presque la même apparence de fraicheur qu’au moment où on l’a cueilli.(…) .» - Réponse de PASTEUR : «Je réponds que le problème doit être facile à résoudre, que vous êtes très bien placé pour tenter une solution, que je vais vous écrire. Bien des idées s’offrent à l’esprit. Voulez-vous tout de suite essayer de tremper les ceps frais dans une solution d’acide borique à 2% et placer en boîte ( ?) comme pour le voyage pendant qques jours. C’est inoffensif et on pourrait recommander un lavage à l’arrivé puis un trempage nouveau dans l’eau pour avant la consommation. Vous m’en exposiez le problème n’est-il pas déjà résolu d’une façon ou d’une autre ?», autre idée de Pasteur : « Essayez également le trempage dans l’eau sans microbe falloir un filtre de porcelaine mais ici le trempage pourrait être prolongé et opérez comme telle comme un deuxième ou troisième trempage » - Puis Pasteur s’enquière de la promotion de Marliave : « J’ai vu M. Liva et lui ai exprimé tout mon chagrin que vous n’ayez pu être décoré. Il en a paru tout aussi désolé aussi si à la prochaine promotion (…)  j’agirai auprès de M. Tisserand avec une insistance particulière Ce 23 juillet 1888… » -  Cette même année, le 14 novembre 1888, est inauguré l’Institut Pasteur en présence du Président Sadi Carnot..

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Pasteur, Louis

French chemist and microbiologist (1822-1895). Visiting card with holograph addidtions (3 lines). With holograph envelope. [Paris] Rue d’Ulm. 32mo. 1 page.
$ 1,592 / 1.400 € (44911)

„LOUIS PASTEUR […] Je remercie bien Richard Emmanuel de sa petite lettre et écrit avec plaisir que je constate des progrès en écriture de en orthographe“.

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Pasteur, Louis

French chemist and microbiologist (1822-1895). Autograph manuscript. N. p. 4to. 1½ pp. on 3 ff.
$ 28,428 / 25.000 € (44140/BN30142)

Notes on silkworm disease. Pasteur compiled the present notes in the Swiss Alps in 1857 with the help of observations made by a silkworm breeder. They contain comparative information on the disease afflicting silkworms and diseases of vineyards and mulberry trees: "Note sur les éducations de vers à soie destinée à la confection de la graine, faite en 1857 dans la Suisse, les montagnes des Basses-Alpes et d'autres localités où l'épidémie n'a pas paru; par M. Guérin [illegible]. […]". Undoubtedly, Pasteur relied on these notes and other accounts when he travelled to the south of France in 1865 to investigate the diseases among silkworms wreaking havoc in the French silk industry, as he had no prior knowledge of the silkworm disease he was comissioned to investigate.

Within three years he succeeded in isolating the bacilli of two distinct diseases and in finding a procedure to prevent contagion as well as in detecting diseased stock. - Slight marginal soiling, otherwise in mint condition..

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Pasteur, Louis

French chemist and microbiologist (1822-1895). Autograph letter signed ("L. Pasteur"). N. p. Large 8vo. ¾ p. on double leaf.
$ 18,194 / 16.000 € (44142/BN30146)

To an unidentified recipient, on how to prevent the spread of rabies: "La loi est formelle. Tout chien mordu par un chien rabique doit être abbatu. Je le vaccinerais que [si] je ne pourrais le rendre à son propriétaire. | L. Pasteur". - Top of fol. 2 with small traces of mounting, otherwise in splendid condition.

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Pasteur, Louis

French chemist and microbiologist (1822-1895). Autograph letter signed ("L. Pasteur"). N. p. Large 8vo. ¾ p.
$ 17,057 / 15.000 € (44143/BN30147)

To an unidentified recipient about an experiment with a rabid dog: "Monsieur, J'ai mis en expérience le bulbe du chien. L'épreuve sera moins sûre que s'il fut mort de mort non violente - un chien mort de rage a toujours la bulbe rabique. Avant la mort il ne l'est pas toujours. Savez l'assurance de ma considération très distinguée". - Small restored tears at edges; somewhat dusty soiled and wrinkled.

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Pasteur, Louis

French chemist and microbiologist (1822-1895). Autograph letter signed ("L. Pasteur"). Paris. Small 8vo. 1 p. With autogr. envelope.
$ 21,036 / 18.500 € (44145/BN30149)

To G. Austin Taylor, on the introduction of rabies in a new country, as related by a Dr. Hampshire: "La question de l'introduction fortuite et relativement récente de la rage dans un pays, telle que vous m'en avez donné connaissance tantôt, en compagnie de Mr le Dr Hampshire est intéressante au point de vue de l'histoire de cette maladie. Permettez-moi de vous prier de demander à Mr le Dr Hampshire de m'en écrire une relation aussi authentique que possible et de la faire traduire en français si ce n'est pas abuser de votre complaisance [...]".

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Pasteur, Louis

French chemist and microbiologist (1822-1895). Autograph manuscript unsigned. [Paris]. 4to (229 x 175 mm). 1 p.
$ 7,391 / 6.500 € (59743/BN44255)

In French: notes on the work of Monsieur Rets entitled 'Present state of studies of silkworms in the Vivrais': "This is what I notice in this note: The few Italian species which, up to now, had resisted the illness and last year had given good results, have now contracted it. They had been left from the early stages by the breeders […] Designation of the species give the best guarantees […] nonetheless there is no sign of any other disease than that of the little ones […] The worms submitted to sulfur and carbon treatment are well up to the present.

The worms are vigorous, healthier, steadier […]". - The present manuscript was written well before Pasteur concentrated his efforts in battling a catastrophic disease of silkworms which was then ruining the production of silk in the south of France during the five-year period from 1865 to 1869. In 1853, silkworm eggs could no longer be produced in France, but had to be imported from Lombardy. The disease then spread to Italy, Spain and Austria. Dealers procuring eggs (i.e., seeds) for the silkworm breeders had to go farther and farther east in an attempt to secure healthy products. The disease followed them, soon engulfing Greece, Turkey, the Caucasus, China and even Japan. By 1865, the silkworm industry in France was near ruin. Though Pasteur had never ever seen a silkworm or a mulberry tree, he began at the request of his master Jean Baptiste Dumas, the famous chemist to investigate the cause of the epidemic. To be of value in his scientific endeavor, Pasteur had to become a masterful industrialist and therefore, it is quite expected that he would criticize those who would be willing to let their own economic failures be dismissed blaming disease rather than their own ineptitude or mismanagement..

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Pasteur, Louis

French chemist and microbiologist (1822-1895). Autograph manuscript unsigned. [Paris. 8vo (210 x 133 mm). 1 p.
$ 4,548 / 4.000 € (59744/BN44256)

A curious manuscript in the hand of Pasteur with fascinating content as the French chemist begins preparations for a lecture: "Do you know what to us is the charm of your studies? Do you know, if you will allow me to speak thus, what is the enchantment of science? It is that we can provide the proof of our principles. Who can give that, this proof of principles, in politics, religion, even in morals? Who can put into the precision of formulas human passions and their sometimes terrible effects, for example the assassination of a Garfield by a dreadful madman […]".

- No doubt Pasteur wrote the present draft in the autumn of 1881 after President James A. Garfield was shot by assassin Charles J. Guiteau, a rejected and disillusioned Federal office seeker on 2 July 1881. Garfield died on 19 September 1881..

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Pasteur, Louis

French chemist and microbiologist (1822-1895). Autograph letter signed ("L. Pasteur"). Paris. 8vo (200 x 130 mm). 1 p.
$ 5,117 / 4.500 € (59745/BN44257)

In French, to an unidentified correspondent: "I do not believe at all that age or youth influences the results of vaccination. If accidents occurred during the night of the vacination, whatever the age of the individual, it was the result of impure vaccine or due to a wrongly performed procedure". - Yellowing, small marginal tears skillfully repaired.

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Pasteur, Louis

French chemist and microbiologist (1822-1895). Autograph letter signed ("L. Pasteur"). [Paris]. 8vo (86 x 114 mm). 1 p.
$ 3,411 / 3.000 € (59746/BN44258)

In French, on his personalized note card (45 Rue d'Ulm), to an unidentified gentleman: "The law is strict: any dog that was bit or in contact with a rabid animal must be killed. Even if I vaccinated them I could not return them to you alive". - Browned, repair to vertical fold.

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Pasteur, Louis

French chemist and microbiologist (1822-1895). Letter signed ("L. Pasteur"). [Paris]. 8vo (178 x 114 mm). 3 pp.
$ 5,117 / 4.500 € (59747/BN44259)

In French, with date, the word "Confidential" and the opening salutation "Dear Doctor" at head of first page in Pasteur's hand. On stationery imprinted with his monogram, to an unidentified doctor: "I would be much obliged to you if you could have the letter enclosed herewith given to Representative Wiedersperg, in relation to the motion he just presented to the Austrian Parliament and that was so successful, as it should have been. I also know that it was put together with you in mind. I have just received from Dr.

Von Frisch the pamphlet containing the sum of his experiments with rabies, a document I have been anxiously awaiting in order to respond to the 16 proposals that appeared in The Medical Week of December 30. What a disappointment! Frisch's pamphlet is so faulty that I will not engage in criticizing it. His experiments and arguments are not worthy of any attention. I will only talk about it if authorized people think it important, no doubt out of ignorance of the issue. That doctor surely deceived me! Since his coming by my laboratory, I had been inclined to consider him an impartial scientist, well versed in experimental practices. I feel disillusioned and, to be brief, I will only give you one justification: he finds Benzi and Amozzo s experiments and their consequences to be good, only too happy to note that they coincide with his own. And when I contradict him with my own positive results and call his negative, he denies me the right to judge his work, and claims that his results are positive. No discussion is possible with a man whose reasoning lacks scientific logic". - Pasteur's own rabies experiments had indeed been successful. In April 1882, he undertook research that proved to be the most spectacular of all-the preventive treatment of rabies. After experimenting with inoculations of saliva from infected animals, he came to the conclusion that the virus was also present in the nerve centers, and he demonstrated that a portion of the medulla oblongata of a rabid dog, when injected into the body of a healthy animal, produced symptoms of rabies. By further work on the dried tissues of infected animals and the effect of time and temperature on these tissues, he was able to obtain a weakened form of the virus that could be used for inoculation. Having detected the rabies virus by its effects on the nervous system and attenuated its virulence, he applied his procedure to man; on 6 July 1885, he saved the life of a nine-year-old boy, Joseph Meister, who had been bitten by a rabid dog. The experiment was an outstanding success, opening the road to protection from a terrible disease..

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Pasteur, Louis

French chemist and microbiologist (1822-1895). Lengthy autograph endorsement and a note signed ("L. P.") on a letter from Dr. G. Rauch. Lisbon. Small folio (267 x 210 mm). 3 pp.
$ 3,980 / 3.500 € (59748/BN44260)

In the present letter, Dr. Rauch requests permission to visit Pasteur's laboratories to examine the discoveries made by one M. Gamaleia in hopes of making a contribution to his work and that of Pasteur. Rauch explains he has had extensive experience with diseases in warm countries, citing two cholera epidemics in Toulon and Algeria and proceeds to list his medical qualifications. He notes he would particularly like to participate in M. Gamaleia s experiments in the endemic field and feels confident that the Minister of the Navy will release him to do so, if accepted.

At the foot of the third page of the letter, Pasteur replies in full from Arbois on 12 September 1888: "Honored Sir and Doctor, As soon as Monsieur Gamaleia has returned to Paris I will hasten to communicate your interesting letter to him. The latter is dated from Lisbon; are you returning on the Brest route, and when? Would you be able to come and see me on your way to Paris where I would perhaps have already returned? We could talk without too much inconvenience to you, about your wishes. Yours truly, L. P." (transl.). A further note in Pasteur's hand is found at the head of the first page of the letter: "To be shown to M. Gamaleia as soon as he arrives. L. P. 12 September 1888". - A fine letter demonstrating Pasteur s great willingness for collaboration between doctors and scientists..

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Pasteur, Louis

French chemist and microbiologist (1822-1895). Letter signed ("L. Pasteur"). Paris. 8vo. 2 pp. on bifolium.
$ 1,706 / 1.500 € (72805/BN46862)

A letter of recommendation to the board of directors of the Exposition Universelle of 1900: "Voulez-vous me permettre de recommander à votre haute bienveillance la candidature de M. Gustave Marchegay qui sollicite la situation d'Inspecteur Principal du service d'architecture des installations à l'Exposition de 1900? [...]". - On headed paper of the Institut Pasteur and receipt stamp.

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Pasteur, Louis

E. beschr. Briefumschlag
Autograph ist nicht mehr verfügbar

Louis Pasteur (1822–1895), Chemiker und Biologe. E. beschriebener Briefumschlag. O. O., 1876. 1 S. Qu.-32°. – „Comptoir commercial et industriel Corse | Carte de M. Oppelt | Bastia | Vins de divers cépages | Reçu la visite de M. Oppelt, le 7 aout 1876 | à Arbois“. – Papierbedingt etwas gebräunt und leicht fleckig.


Pasteur, Louis

Albumblatt mit eigenh. U.
Autograph ist nicht mehr verfügbar

Louis Pasteur (1822–1895), Chemiker und Biologe. Albumblatt mit e. U. O. O., 31. Oktober 1893. ½ S. 8°. – „L. Pasteur | de l’Institut de France avec tous ses compliments [...]“. – Mit dünner Feder auf leicht gebräuntem Papier; die Verso-Seite mit kleinen Montagespuren.


Pasteur, Louis

Eigenh. Visitenkarte mit Initialen.
Autograph ist nicht mehr verfügbar

Confirms the receipt of the „Quarterly Journal of Microscopic Science“ (issue from April 1878) by Monsieur Chèreau: „Reçu de M. Chèreau le 9 julliet 1878 no. avril 1878 du Quarterly Journal of microsc. Sci. | LP“. – On the printed page Pasteur notices: „M. Chèreau [...] avec mille remerciements TSVP [tirez s’il vous plaît]“. – In pencil.


Pasteur, Louis

E. Billet auf seiner Visitenkarte
Autograph ist nicht mehr verfügbar

Louis Pasteur (1822-1895), französischer Chemiker und Biologe; schuf die Grundlagen der Bakteriologie. E. Billett auf seiner Visitenkarte, Arbois (Jura), o. D., eine Seite Visitformat. „LOUIS PASTEUR | MEMBRE DE L’INSTITUT | avec ses très sincères et affectueux remerciements“.


Pasteur, Louis

Signed cabinet photograph.
Autograph ist nicht mehr verfügbar


Pasteur, Louis

Kabinettfotografie m. e. U.
Autograph ist nicht mehr verfügbar

Louis Pasteur (1822–1895), chemist. Cabinet photograph signed on the backing board. [Paris, c. 1889]. 10.7 x 16.3 cm. All edges gilt. Expressive oval head-and-shoulders portrait by Pierre Petit, Paris.


Pasteur, Louis

E. Briefumschlag
Autograph ist nicht mehr verfügbar

Louis Pasteur (1822-1895), Chemiker. E. Briefumschlag, Paris, o. D., 1 Seite quer-12°. Gebräunt; mit fehlendem Eckchen. „Monsieur A. Cahoun | Monnaie, Quai Conti | Paris“.